One problem is that we are trying to symbolize, in a way usable in all or most cases, the function of an extremely complex organ-- whose state and function in the past we cannot know post-fact.
Saying, "Stuff happened in his brain, and so he stabbed his mother to death" isn't necessarily more useful than "He with malice and intent did plunge his knife through his mother's heart." Unless you know exactly what stuff, and how to fix his behavior so that it will be guaranteed to be acceptable in the future, the philosophical belief/understanding of physical determinism doesn't really tell us how to go ahead.
Saying, "Stuff happened in his brain, and so he stabbed his mother to death" isn't necessarily more useful than "He with malice and intent did plunge his knife through his mother's heart." Unless you know exactly what stuff, and how to fix his behavior so that it will be guaranteed to be acceptable in the future, the philosophical belief/understanding of physical determinism doesn't really tell us how to go ahead.