pmdd

[brewer]

And then we get into a whole new debate on allergy and what "allergy" actually means. I think your definition and the definition of allergy used here is old school. If you think that" allergy" refers to only IgE mediated allergies then we disagree on the terminology but I'm sure we would have to agree to disagree on it.

An excerpt...

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In non-IgE-mediated allergy, the antibody may belong to the IgG isotype, as in anaphylaxis due to immune complexes containing dextran (32) and the classical, now rare, serum sickness previously referred to as a type III reaction (25), whereas both IgE and IgG antibodies are found in allergic bronchopulmonary aspergillosis (ABPA) (68).
Inhalation of large amounts of protein, as in mold, grain dust, etc., stimulates the immune system to produce antibodies mainly of the IgG, IgA, and IgM isotype. The serum concentration is often high enough to allow detection of the antibody, historically termed “precipitin”, as a precipitate in gel when allowed to react with the corresponding antigen. There is a relation between degree of exposure and antibody concentration. Similarly, the presence in serum of IgA, IgM, and especially IgG antibodies, as a result of exposure but without any obvious pathogenic role, has also been reported to food antigens, such as those of cow's milk and hen's egg (39). In the same way, antigen-specific lymphocytes can often be found by using the antigen-specific lymphocyte stimulation test (50, 71).
Some individuals with high IgG antibody levels as a result of chronic inhalation of large amounts of certain protein-containing material, such as Actinomyces and molds (farmer's lung) and bird droppings (pigeon breeder's disease), may exhibit symptoms from the airways, often referred to as “alveolitis”, upon exposure. We propose that the term allergic alveolitis be used for such diseases.
Allergy can also be cell-mediated, as in allergic contact dermatitis, in which immunologically sensitized lymphocytes play a major role. Similar immunologic mechanisms seem to be important in celiac disease (29) and in non-IgE-associated “atopic dermatitis/eczema” (see below). Therefore, we propose that non-IgE-mediated allergic reactions be subdivided into those in which the reaction is initiated predominantly by mechanisms associated with allergen-specific antibodies other than IgE, and those in which a cellular response is predominant.

http://onlinelibrary.wiley.com/doi/10.1111/j.1398-9995.2001.00002.x-i1/full

I think it's likely to be a cell mediated non IgE " reaction" " allergy" " hypersensitivity or whatever you prefer to call it. 

I have however read a story once about a woman who apparently was so "allergic" to progesterone she would have anaphylaxis during pms. She did actually have to have her ovaries removed.

Your comment about the eggs... its odd that you would perceive that I was referring to post surgery not pre surgery. Was it something in the way I wrote it or the way you interpreted it? My statement refers to the idea that if mom and grandma bleed well into thier 50's there may be another 10 years of eggs hanging around in a woman in thier 40's. Thats 10 years worth of hormone protection from advanced aging that one sacrifices for happiness. You may find that the trade off for such serenity is osteoporosis... not to mention, the fires that makes one sexy like shiney hair, unwrinkled skin etc...

You cant stay on lupron for the rest of your life. It's simply used as a trial to see if you are a good candidate for getting oophed. 

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I think it boils down to this

Treat the neurotransmitters with antidepressants
or
Pull the plugs on the cause ( the ovaries that produce the offending hormones )

My point is that woman should have that option, long before their lives have been destroyed. But Big pharma makes much more money off option one. 

Maybe they will change their stand when they use their logic to realize they can really profit off osteoporosis.

When all is said and done, the truth can always been found in the most up to date hoarded patents. I will check them out later. I will look for better links on the allergy theory as well... probably wont find much for another 5-10 years.

In regards to your comnent about thyroid issues, yes agreed, but your original definition of the ovarian hypothesis was wrong as it inferred an imbalance so my comment was in regards to your position.

It's a womans problem because it happens to woman and even if it was due to testosterone, it would still be a womans problem...

Moderator Notice
If you post an excerpt, post it as a quote and give clear credit to whomever actually wrote it, otherwise it's plagairism. If you make a huge post, hide tags are your friend.

I'll wait for your allergy source. Not even contemplating your "belief". PMS anaphylaxis, source please. Or is this an anecdote?

Do you know the cost/profit associated with pre/post surgery related medications?  They do profit from osteoporosis prevention medication. Look it up.

You can stay on Lupron for life. Look it up. Oh hell: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193774/

As for the eggs and 10 years of hormone production, so? Back to make a risk vs benefit analysis on selecting a treatment.

The "ovarian hypothesis" was not my definition. That was the source. So you went out of your way to comment on a model that is not current. Great.

Yes, it's a woman's problem. What's your point? Impotence after prostate surgery is a mans problem. Again, what's the point?