The Islamic prophet's foreknowledge of the Terfeziaceae's health benefits

[Astreja]

Microorganisms were discovered for the first time in the 17th century, almost one thousand years after Muhammad's death, and almost 800 years after Al-Bukhari compiled his famous hadith collection. There is no way anyone back then could have investigated some antimicrobial effect of truffles.

People didn't need to know about the existence of microbes. The use of plants for medicinal purposes goes back thousands of years, long before the hadiths. They didn't need to know how it worked, only that it did work, and that knowledge would get passed down to a new generation of herbalists. The lack of a scientific explanation doesn't stop a remedy from working.