A knockdown prophecy

[R00tKiT]

No, there isn't.  Evolution doesn't work that way.  One could always say "modern humans have gene ABC, and pre-humans didn't", but then you would probably find some modern humans that don't have gen ABC either, and that gene might end up being found in some ancient hominids in some degree.

That's because you didn't accurately define what the word "modern human" means, once you stick to a definition, there is necessarily a first human who fits the definition.

But yeah, you always win if you keep changing definitions.