Well if you are really concerned with your brain and it's future scientifically it is always safer to not use drugs. That is across the board.
If you are concerned about having a good time in the short term, it's great. The hangover is fairly gnarly though. I wouldn't bother with the alcohol, it dilutes the pure high.
If you are concerned about having a good time in the short term, it's great. The hangover is fairly gnarly though. I wouldn't bother with the alcohol, it dilutes the pure high.