Well you would have to show that the "soul" exists even when the brain dies. We have all sorts of evidence that brain death is the end of the individual. We have further evidence that damage to different parts of the brain affect an individual's ability to function, the more damage the greater the effect. With that in mind the function of the soul (in terms of how much of you would be in it) appears VERY limited. The soul wouldn't have memory - we know that's in the brain, or language skills or motor skills (obviously).
What does that leave? Judging by severe cases of diseases like Alzheimers - not much.
What does that leave? Judging by severe cases of diseases like Alzheimers - not much.