RE: Serotonin question
April 8, 2014 at 9:20 am
(This post was last modified: April 8, 2014 at 9:36 am by Ksa.)
(April 7, 2014 at 9:59 pm)Senshi Wrote:(April 1, 2014 at 2:53 pm)Ksa Wrote: Was wondering if anyone has an equation for the rate of decay of Serotonin following a near Serotonin Syndrome (drug induced) event where no treatment was provided except for the temporary discontinuation of serotonergic agents and tryptophan supplements.
I also welcome rough estimates if you're a specialist, thank you!
Quote: the rate of decay of Serotonin following a near Serotonin Syndrome (drug induced)
The chemical rate of decay of Serotonin has nothing to do with any of your syndromes!
Do you mean to ask "how long will the current supply in my body last?"
That depends on how many receptors you have for it, your bodies specific reuptake rate, and the amount of (5-HIAA) your body currently has, AND, how fast your body produces and processes all of these chemicals. And, that depends on other variables such as physical activity, mood, and diet.
Please devellop, I found this which is in accordance with what you say:
Quote:LABORATORY EVALUATION — Serotonin syndrome is a clinical diagnosis; serum serotonin concentrations do not correlate with clinical findings, and no laboratory test confirms the diagnosis [3]. Nevertheless, some nonspecific laboratory findings may develop, including an elevated white blood cell count, elevated creatine phosphokinase, and decreased serum bicarbonate concentration.
I assume that means some patients with serotonin syndrome do not feature high serum serotonin levels?
![[Image: Untitled_1.jpg]](https://images.weserv.nl/?url=s7.postimg.org%2Fmvlqt55mj%2FUntitled_1.jpg)