I've been through it a few times, en route from Pittsburgh to E. Lansing and Ann Arbor. It's certainly a bit rough in areas. IIRC around the north of the city in particular (Eight Mile/M-102?). As a southern Californian, in this "perpetually great" weather of ours, parts of L.A. freak me out even more.
"For me, it is far better to grasp the Universe as it really is than to persist in delusion, however satisfying and reassuring." - Carl Sagan