(July 24, 2015 at 12:58 am)RandomPastaFan Wrote: It does not seem there where any follow up research available for public viewing but medical study can take long periods of time and have lots of ethics to consider.
Infirmity is also linked to the bone degeneration process that happens, can be slowed with exercise and weight bearing activities.
NAD also being used in the Krebs cycle and Electron transport chain it could very well lead to problems.
retirement age unlikely due to retirement not just being due to the break down of muscle but the degeneration of tissue and mental cognitive function.
that last one is difficult to answer as it depends on the person. Do they have medical conditions . But if there was an increase in muscular strength it would reduce the risk of injury in elderly because of the loss of strength can be one factor that does impact on injury rate.
sorry I can't provide links at this stage.
Trust me I understand about links, heck, I've been speaking without links myself mostly since most of this is just from my memory. I don't expect extra NAD+ should be a problem, since it is basically a spectator in metabolism, ferrying along electrons. Excess of the NAD+ form could encourage glycolysis, gluconeogenesis, etc., but that should actually help I'd bet, providing greater cellular endurance, assuming a proper energy supply. Retirement age was mostly a moot point, but I almost wonder since retirement age seems to correlate loosely with average life-span, and of course it should depending on your time-frame. I do agree that injury depends on person to person, but I wonder if a youth-like body (strength and endurance) combined with an aged mind would potentially lead to a large increase of injury from risky behavior in patients. Ugh, I hate medicine and their "potentially" crap, I'm a biochemist, and I prefer "actually."
