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How are drugs made?
#6
RE: How are drugs made?
This is what I do for a living. Here's a super over-simplified bullet point list of the general process of drug discovery and development:

-A need is identified. New antibiotic, cancer drug, antidepressant, boner pill, etc.
-A mode of action is identified that identifies drug candidates. (if a chemical kills certain cells or causes cells or systems to behave in the desired way, etc)
-A screen is designed to exploit this mode of action (a receptor is cloned onto a cell line, or a cell line/organism is propagated, or some other relevant biological parameter is cultured or manufactured).
-Random or targeted chemistry is screened using the assays that were designed above.
-Classes of chemistry that do the desired thing in your screen are identified and chemistry wizardry and art is applied to making different molecules based on that class of chemistry
-Leads are identified and tested more rigorously for efficacy and safety
-New drug is chosen from field of candidates and is tested in the field in clinical trials
-New drug on TV, where you are directed to discuss it with your doctor. Smile

There are, as you imagine, quite a few details in between.
If The Flintstones have taught us anything, it's that pelicans can be used to mix cement.

-Homer Simpson
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Messages In This Thread
How are drugs made? - by Heat - October 25, 2015 at 12:44 am
RE: How are drugs made? - by Silver - October 25, 2015 at 12:45 am
RE: How are drugs made? - by Heat - October 25, 2015 at 12:49 am
RE: How are drugs made? - by Ravenshire - October 25, 2015 at 1:16 am
RE: How are drugs made? - by Heat - October 25, 2015 at 1:22 am
RE: How are drugs made? - by Cato - October 25, 2015 at 7:23 am
RE: How are drugs made? - by Mermaid - October 25, 2015 at 4:28 am
RE: How are drugs made? - by vorlon13 - October 25, 2015 at 9:54 am

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