The Principle of Contingent Causation: The Impossibility of Infinite Regress.

[Deesse23]

As far as I can tell, nothing Penrose says speaks at all against an essential First Cause. Or something like the Neoplatonic One, or the Brahman, or the Buddhist Not-Two. 

...or pink unicorns.

Looks like someone is trying to shift the burden of proof. Nobody needs to falsify your argument. However YOU need to demonstrate that even the premises of it (like causation) are valid.