Big difference is that science has an in-built mechanism for correcting errors, false data or deliberate lies. There is nothing in religion that even comes close.
At the age of five, Skagra decided emphatically that God did not exist. This revelation tends to make most people in the universe who have it react in one of two ways - with relief or with despair. Only Skagra responded to it by thinking, 'Wait a second. That means there's a situation vacant.'