Well, as I recall - dimly - it was a combination of the antipsychotics and the antidepressants, or at least their "uncommon" side effects. Something like that anyway.
At the age of five, Skagra decided emphatically that God did not exist. This revelation tends to make most people in the universe who have it react in one of two ways - with relief or with despair. Only Skagra responded to it by thinking, 'Wait a second. That means there's a situation vacant.'