I've been playing around with different builds and self-imposed restrictions in Fallout 4. (Restrictions like no settlements, using vendors, crafting, etc)
I've been playing with different iterations of a junkie build, which is built around using a weapon with the Junkies legendary effects and maximizing the number of debuffs from addictions to increase the damage done. The upside is that you can do ridiculous damage (150% junkie bonus with 12 addictions), but VATS is pretty useless due to agility (along with everything else) getting debuffed into oblivion. Fun stuff.
I've been playing with different iterations of a junkie build, which is built around using a weapon with the Junkies legendary effects and maximizing the number of debuffs from addictions to increase the damage done. The upside is that you can do ridiculous damage (150% junkie bonus with 12 addictions), but VATS is pretty useless due to agility (along with everything else) getting debuffed into oblivion. Fun stuff.