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How are drugs made?
#1
How are drugs made?
Prescription drugs, I am curious about learning how scientists engineer drugs, like for example ADHD medication(which I take), or in general. What's the process, like how do they design them, how do they figure out what chemicals to put in, etc.

If someone could link me to a website explaining this, or youtube video preferably, that would be great, i'm just interested. No, i'm not talking about illegal drugs, i'm not trying to learn this so I can go make meth, lol. Just curious.
Which is better:
To die with ignorance, or to live with intelligence?

Truth doesn't accommodate to personal opinions.
The choice is yours. 
--------------------------------------------------------------------------------

There is God and there is man, it's only a matter of who created whom

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The more questions you ask, the more you realize that disagreement is inevitable, and communication of this disagreement, irrelevant.
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#2
RE: How are drugs made?
You can't do an engine search yourself?
"Never trust a fox. Looks like a dog, behaves like a cat."
~ Erin Hunter
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#3
RE: How are drugs made?
(October 25, 2015 at 12:45 am)Kitan Wrote: You can't do an engine search yourself?
I have, both on google, and on youtube, on google all that I see is how to make illegal drugs, on youtube it's just video's telling me how illegal drugs effect the brain, anything on google that's not about something illegal is about the side effects of prescription medications.

Nothing i'm looking for..
Which is better:
To die with ignorance, or to live with intelligence?

Truth doesn't accommodate to personal opinions.
The choice is yours. 
--------------------------------------------------------------------------------

There is God and there is man, it's only a matter of who created whom

---------------------------------------------------------------------------------
The more questions you ask, the more you realize that disagreement is inevitable, and communication of this disagreement, irrelevant.
Reply
#4
RE: How are drugs made?
That was difficult. [Image: free-rolleye-smileys-323.gif]

https://www.google.com/?gws_rd=ssl#q=how...drugs+made
Thief and assassin for hire. Member in good standing of the Rogues Guild.
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#5
RE: How are drugs made?
(October 25, 2015 at 1:16 am)SnakeOilWarrior Wrote: That was difficult. [Image: free-rolleye-smileys-323.gif]

https://www.google.com/?gws_rd=ssl#q=how...drugs+made
I swear I never saw half the links on that when I searched it..
Maybe I searched for something different..thanks i guess...
Which is better:
To die with ignorance, or to live with intelligence?

Truth doesn't accommodate to personal opinions.
The choice is yours. 
--------------------------------------------------------------------------------

There is God and there is man, it's only a matter of who created whom

---------------------------------------------------------------------------------
The more questions you ask, the more you realize that disagreement is inevitable, and communication of this disagreement, irrelevant.
Reply
#6
RE: How are drugs made?
This is what I do for a living. Here's a super over-simplified bullet point list of the general process of drug discovery and development:

-A need is identified. New antibiotic, cancer drug, antidepressant, boner pill, etc.
-A mode of action is identified that identifies drug candidates. (if a chemical kills certain cells or causes cells or systems to behave in the desired way, etc)
-A screen is designed to exploit this mode of action (a receptor is cloned onto a cell line, or a cell line/organism is propagated, or some other relevant biological parameter is cultured or manufactured).
-Random or targeted chemistry is screened using the assays that were designed above.
-Classes of chemistry that do the desired thing in your screen are identified and chemistry wizardry and art is applied to making different molecules based on that class of chemistry
-Leads are identified and tested more rigorously for efficacy and safety
-New drug is chosen from field of candidates and is tested in the field in clinical trials
-New drug on TV, where you are directed to discuss it with your doctor. Smile

There are, as you imagine, quite a few details in between.
If The Flintstones have taught us anything, it's that pelicans can be used to mix cement.

-Homer Simpson
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#7
RE: How are drugs made?
(October 25, 2015 at 1:22 am)heatiosrs Wrote:
(October 25, 2015 at 1:16 am)SnakeOilWarrior Wrote: That was difficult. [Image: free-rolleye-smileys-323.gif]

https://www.google.com/?gws_rd=ssl#q=how...drugs+made
I swear I never saw half the links on that when I searched it..
Maybe I searched for something different..thanks i guess...
This is what you're really after then. A menu of links to several fine articles on the art of database searching.

http://www.askscott.com/tindex.html
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#8
RE: How are drugs made?
Reprisol remains a hypothetical drug . . .
 The granting of a pardon is an imputation of guilt, and the acceptance a confession of it. 




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