Are lockdowns justified?

[Anomalocaris]

This makes about as much sense as saying that, since female turkeys (or bees...) do not need males to procreate, turkey as a species could survive even if all males were killed. No, self-replication leads to harmful mutation building up even more so than inbreeding does.

Uh, no, Species that rely on self replicate tend to die out not because accumulation of harmful mutations.

mutations that menifest harmful traits don’t tend to accumulate because they kill the host, hence no accumulation. remember?

Actually, species that rely on self replication dies out because they can’t mutate fast enough, not because they accumulate too many harmful mutations.

You see, If you start out with 10 individuals in a self replicating specie with 10 different genomes, and each of them have 10 offsprings. The next generation there are 100 individuals but still just 10 different genomes. Next generation you have 1000 individuals, and yes, you guessed it, still just 10 different genomes. Say you have a new mutation somewhere, oh, zip a dee dooo! You now have 11 different genomes. If a nasty thing, like a disease or a major environment change, comes their way, they have 10, or with a mutation, 11 different shots at having a genome that can deal with the challenge. Now start with 10 breeding individuals in a breeding species, and each pair have 10 offsprings. The next generation you only have 50 individuals. But because each individual’s genome is a different combination of the parents’ genome, everyone of the 50 individual have a different genome, you now have 50 different genomes. Next generation, you have 250 individual, and 250 genomes. If a nasty thing comes, they have 250 different shots at having a genome that can deal with the challenge.

Hence a breeding specie generates exponentially more genetic variation than a strictly self-replicating specie. It is the volume of genetic variation, or genetic diversity within a specie, that allows a specie to better adapt to changing environment.

Diversity is in principle good, in a gene pool, or on a meme pool, as in a culture pool. idiotic conservatives and troglodyte nativists take note.

[The Architect Of Fate]

As for the question of why viruses can leap hosts and why recombination does not result in a massive amount of genetic degradation  

1. Recombination isn't required for a virus to leap hosts as some viruses are able to infect a new host anyway. Coronaviruses are particularly good at this.


2. Viruses create a lot of De Novo genetic diversity.


3.Bad mutations tend to be eliminated by natural selection

[BrianSoddingBoru4]

This makes about as much sense as saying that, since female turkeys (or bees...) do not need males to procreate, turkey as a species could survive even if all males were killed. No, self-replication leads to harmful mutation building up even more so than inbreeding does.

Uh, no,  Species that rely on self replicate tend to die out not because accumulation of harmful mutations.    

mutations that menifest harmful traits don’t tend to accumulate because they kill the host, hence no accumulation.   remember?

Actually, species that rely on self replication dies out because they can’t mutate fast enough, not because they accumulate too many harmful mutations.    

You see,     If you start out with 10 individuals in a self replicating specie with 10 different genomes, and each of them have 10 offsprings.   The next generation there are 100 individuals but still just 10 different genomes.   Next generation you have 1000 individuals, and yes, you guessed it, still just 10 different genomes.    Say you have a new mutation somewhere, oh, zip a dee dooo!  You now have 11 different genomes.    If a nasty thing, like a disease or a major environment change, comes their way, they have 10, or with a mutation, 11 different shots at having a genome that can deal with the challenge.     Now start with 10 breeding individuals in a breeding species, and each pair have 10 offsprings.    The next generation you only have 50 individuals.   But because each individual’s genome is a different combination of the parents’ genome, everyone of the 50 individual have a different genome, you now have 50 different genomes.    Next generation, you have 250 individual, and 250 genomes.   If a nasty thing comes, they have 250 different shots at having a genome that can deal with the challenge.

Hence a breeding specie generates exponentially more genetic variation than a strictly self-replicating specie.   It is the volume of genetic variation, or genetic diversity within a specie, that allows a specie to better adapt to changing environment.    

Diversity is in principle good, in a gene pool, or on a meme pool, as in a culture pool.   idiotic conservatives and troglodyte nativists take note.

Just an aside, as it's driving me spare: The singular of 'species' is 'species', not 'specie'.

You may now return to handing FA his own arse.

Boru

[FlatAssembler]

I asked that question about inbreeding of viruses on Quora and I received some very complicated response:

Contrary to a couple of answers, recombination between viruses can occur if two closely related viruses co-infect the same cell

Influenza viruses have a segmented RNA genome - each gene on its own RNA molecule. It is nit hard to see that if two such viruses co-infect a cell, the viral packaging equipment cannot tell which parental virus a copy is from. This mechanism accounts for some of the large antigenic “shifts”

Coronaviruses have a single RNA molecule as a genome, but to express many of its genes it must make partial copies of the genome that all share a common 5’ leader. These are crates by a discontinuous replication process - the viral replicase complex pauses and then jumps to another portion of the template and restarts. This jump is not restricted to the same RNA - “template switching” can occur and so recombination can occur

But as Adam Wu neatly pointed out, coronaviruses are haploid so the whole concept of inbreeding doesn’t apply. Any recombined viruses that are lacking critical components will quickly die off.

Do you think that is science or that it is just a theory? If it is science, could you say it in a more layman terminology for me?

[BrianSoddingBoru4]

I asked that question about inbreeding of viruses on Quora and I received some very complicated response:

Contrary to a couple of answers, recombination between viruses can occur if two closely related viruses co-infect the same cell

Influenza viruses have a segmented RNA genome - each gene on its own RNA molecule. It is nit hard to see that if two such viruses co-infect a cell, the viral packaging equipment cannot tell which parental virus a copy is from. This mechanism accounts for some of the large antigenic “shifts”

Coronaviruses have a single RNA molecule as a genome, but to express many of its genes it must make partial copies of the genome that all share a common 5’ leader. These are crates by a discontinuous replication process - the viral replicase complex pauses and then jumps to another portion of the template and restarts. This jump is not restricted to the same RNA - “template switching” can occur and so recombination can occur

But as Adam Wu neatly pointed out, coronaviruses are haploid so the whole concept of inbreeding doesn’t apply. Any recombined viruses that are lacking critical components will quickly die off.

Do you think that is science or that it is just a theory? If it is science, could you say it in a more layman terminology for me?

In layman’s terms, it means you were wrong.

Boru

[Angrboda]

I asked that question about inbreeding of viruses on Quora and I received some very complicated response:
Do you think that is science or that it is just a theory? If it is science, could you say it in a more layman terminology for me?

In layman’s terms, it means you were wrong.

Boru

Yes, and no. It does seem from the answer that some cross-contamination of genetic material can occur. What was he wrong about?

[BrianSoddingBoru4]

In layman’s terms, it means you were wrong.

Boru

Yes, and no.  It does seem from the answer that some cross-contamination of genetic material can occur.  What was he wrong about?

That corona virus should die out via inbreeding.

But as Adam Wu neatly pointed out, coronaviruses are haploid so the whole concept of inbreeding doesn’t apply. 

Boru

[Anomalocaris]

In layman’s terms, it means you were wrong.

Boru

Yes, and no.  It does seem from the answer that some cross-contamination of genetic material can occur.  What was he wrong about?

No one ever said cross contamination can not occur.   Where he is wrong, several times over, is in asserting that is like inbreeding, which implies cross contamination leads to 1)harmful mutations accumulating and 2) manifesting, 3) in a way that would not occur without cross conteminatiom.    This is 1) wrong, 2) wrong, 3) wrong.