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Are lockdowns justified?
RE: Are lockdowns justified?
Quote:This makes about as much sense as saying that, since female turkeys (or bees...) do not need males to procreate, turkey as a species could survive even if all males were killed. No, self-replication leads to harmful mutation building up even more so than inbreeding does.



Uh, no, Species that rely on self replicate tend to die out not because accumulation of harmful mutations.

mutations that menifest harmful traits don’t tend to accumulate because they kill the host, hence no accumulation. remember?

Actually, species that rely on self replication dies out because they can’t mutate fast enough, not because they accumulate too many harmful mutations.

You see, If you start out with 10 individuals in a self replicating specie with 10 different genomes, and each of them have 10 offsprings. The next generation there are 100 individuals but still just 10 different genomes. Next generation you have 1000 individuals, and yes, you guessed it, still just 10 different genomes. Say you have a new mutation somewhere, oh, zip a dee dooo! You now have 11 different genomes. If a nasty thing, like a disease or a major environment change, comes their way, they have 10, or with a mutation, 11 different shots at having a genome that can deal with the challenge. Now start with 10 breeding individuals in a breeding species, and each pair have 10 offsprings. The next generation you only have 50 individuals. But because each individual’s genome is a different combination of the parents’ genome, everyone of the 50 individual have a different genome, you now have 50 different genomes. Next generation, you have 250 individual, and 250 genomes. If a nasty thing comes, they have 250 different shots at having a genome that can deal with the challenge.

Hence a breeding specie generates exponentially more genetic variation than a strictly self-replicating specie. It is the volume of genetic variation, or genetic diversity within a specie, that allows a specie to better adapt to changing environment.

Diversity is in principle good, in a gene pool, or on a meme pool, as in a culture pool. idiotic conservatives and troglodyte nativists take note.
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RE: Are lockdowns justified?
As for the question of why viruses can leap hosts and why recombination does not result in a massive amount of genetic degradation  

1. Recombination isn't required for a virus to leap hosts as some viruses are able to infect a new host anyway. Coronaviruses are particularly good at this.


2. Viruses create a lot of De Novo genetic diversity.


3.Bad mutations tend to be eliminated by natural selection
"Change was inevitable"


Nemo sicut deus debet esse!

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 “No matter what men think, abortion is a fact of life. Women have always had them; they always have and they always will. Are they going to have good ones or bad ones? Will the good ones be reserved for the rich, while the poor women go to quacks?”
–SHIRLEY CHISHOLM


      
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RE: Are lockdowns justified?
(April 27, 2021 at 8:31 pm)Anomalocaris Wrote:
Quote:This makes about as much sense as saying that, since female turkeys (or bees...) do not need males to procreate, turkey as a species could survive even if all males were killed. No, self-replication leads to harmful mutation building up even more so than inbreeding does.



Uh, no,  Species that rely on self replicate tend to die out not because accumulation of harmful mutations.    

mutations that menifest harmful traits don’t tend to accumulate because they kill the host, hence no accumulation.   remember?

Actually, species that rely on self replication dies out because they can’t mutate fast enough, not because they accumulate too many harmful mutations.    

You see,     If you start out with 10 individuals in a self replicating specie with 10 different genomes, and each of them have 10 offsprings.   The next generation there are 100 individuals but still just 10 different genomes.   Next generation you have 1000 individuals, and yes, you guessed it, still just 10 different genomes.    Say you have a new mutation somewhere, oh, zip a dee dooo!  You now have 11 different genomes.    If a nasty thing, like a disease or a major environment change, comes their way, they have 10, or with a mutation, 11 different shots at having a genome that can deal with the challenge.     Now start with 10 breeding individuals in a breeding species, and each pair have 10 offsprings.    The next generation you only have 50 individuals.   But because each individual’s genome is a different combination of the parents’ genome, everyone of the 50 individual have a different genome, you now have 50 different genomes.    Next generation, you have 250 individual, and 250 genomes.   If a nasty thing comes, they have 250 different shots at having a genome that can deal with the challenge.

Hence a breeding specie generates exponentially more genetic variation than a strictly self-replicating specie.   It is the volume of genetic variation, or genetic diversity within a specie, that allows a specie to better adapt to changing environment.    

Diversity is in principle good, in a gene pool, or on a meme pool, as in a culture pool.   idiotic conservatives and troglodyte nativists take note.

Just an aside, as it's driving me spare: The singular of 'species' is 'species', not 'specie'.

You may now return to handing FA his own arse.

Boru
‘I can’t be having with this.’ - Esmeralda Weatherwax
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RE: Are lockdowns justified?
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RE: Are lockdowns justified?
‘I can’t be having with this.’ - Esmeralda Weatherwax
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RE: Are lockdowns justified?
(April 28, 2021 at 11:17 am)BrianSoddingBoru4 Wrote:
(April 28, 2021 at 10:51 am)FlatAssembler Wrote: I asked that question about inbreeding of viruses on Quora and I received some very complicated response:
Do you think that is science or that it is just a theory? If it is science, could you say it in a more layman terminology for me?

In layman’s terms, it means you were wrong.

Boru

Yes, and no. It does seem from the answer that some cross-contamination of genetic material can occur. What was he wrong about?
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RE: Are lockdowns justified?
(April 28, 2021 at 11:37 am)Angrboda Wrote:
(April 28, 2021 at 11:17 am)BrianSoddingBoru4 Wrote: In layman’s terms, it means you were wrong.

Boru

Yes, and no.  It does seem from the answer that some cross-contamination of genetic material can occur.  What was he wrong about?

That corona virus should die out via inbreeding.

Quote:But as Adam Wu neatly pointed out, coronaviruses are haploid so the whole concept of inbreeding doesn’t apply. 


Boru
‘I can’t be having with this.’ - Esmeralda Weatherwax
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RE: Are lockdowns justified?
(April 28, 2021 at 11:37 am)Angrboda Wrote:
(April 28, 2021 at 11:17 am)BrianSoddingBoru4 Wrote: In layman’s terms, it means you were wrong.

Boru

Yes, and no.  It does seem from the answer that some cross-contamination of genetic material can occur.  What was he wrong about?

No one ever said cross contamination can not occur.   Where he is wrong, several times over, is in asserting that is like inbreeding, which implies cross contamination leads to 1)harmful mutations accumulating and 2) manifesting, 3) in a way that would not occur without cross conteminatiom.    This is 1) wrong, 2) wrong, 3) wrong.
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