Transcendental Knowledge?

[Neo-Scholastic]

...The fact that mathematics break down in the case of Singularities, however, casts doubt in my mind that even mathematics, though accurately descriptive about the reality within which our brains evolved to take advantage of, itself can be said to contain explanatory power, or necessary truths, about more fundamental levels of reality.

If that is indeed a fact then all bets are off and the very possibility of knowledge is in question, yes?[/quote]