Does Physics now have a complete description of Nature?

[Anomalocaris]

Has basic Science now ended?  In other words, are QED (Quantum Electrodynamics), QCD and General Relativity basically complete theories and there really is no hope of anything beyond those?  Or, will String Theory, M Theory, or some successor theory unite all theories into something even greater, something that leads to testable predictions?  Or, as Sean Carroll says, does it even matter:

Ahem.

This equation does not allow for flightless waterfowl.

The opus term was dropped when it was found to be aesthetically displeasing to the string theorists because it threaten to produce testable local predictions in bloom county.