I guess I really don't pay a whole lot of attention to music in games, but the one that really stands out to me was the original Metroid. It made great for great atmosphere, and it was quite brilliant for the 8-bit generation it came from.
Even if the open windows of science at first make us shiver after the cozy indoor warmth of traditional humanizing myths, in the end the fresh air brings vigor, and the great spaces have a splendor of their own - Bertrand Russell