If someone says science can't explain everything what's the best way to repond?

[MJ the Skeptical]

To me it's always been like this, if we can't use the rigorous standards within the scientific method to figure it all out then nothing at present moment can. Until some other form of empirical self correcting, problem solving method comes along nothing will ever produce results like we get with the scientific method, nothing. You'll get a nobel prize for discovering something more sturdy than science. If you're in doubt of something, always get your postulations peer reviewed.