I'd have to say that my favorite is "cunt." The power of swear words comes from their ability to offend people with fragile sensibilities, and we have started to become too desensitized to "fuck." It is my number two favorite swear word due to its versatility, but nothing beats watching jaws drop when you call someone a cunt.
Even if the open windows of science at first make us shiver after the cozy indoor warmth of traditional humanizing myths, in the end the fresh air brings vigor, and the great spaces have a splendor of their own - Bertrand Russell