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Interesting snippet on Tx resistent depression.
#61
RE: Interesting snippet on Tx resistent depression.
I'm looking forward to pictures of his diet ... and a link to his CV.

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#62
RE: Interesting snippet on Tx resistent depression.
(August 29, 2016 at 7:55 am)LadyForCamus Wrote: Okay...so you're NOT a dietitian then?  Because, I can see how a layperson may be confused considering how you've posted about the subject in this thread.

Please, only dispense nutritional recommendations once you have completed the required education and professional training to do so.  Otherwise, I'm going to start telling people how to cut down trees and you, as the professional, can let me know what you think about me doing that.  Yeah?

[emoji57]

Also...I like your tree carving; it's pretty awesome.  
I've completed a 3 month course of colon cleansing, body ph readjustment, and change of gut biome. I directly experienced the difference in mood, emotion and mental clarity. I was like my body was rejoicing underneath me. I've also experienced the decline of natural elation and clarity as my diet turned back to crap. I have lived through what I assert.

Does it take a PHD to know fresh food is good for you and processed food full of sugar and chemical preservatives is bad for you? I also link a number of medical doctors and specialist that said "your gut health does affect your overall sense of well being." Plus the science of how/why it affects you. If you want to appeal to authority, it's all there to find.

BTW, do you know what you body does to protect itself against highly acidic stomach acid?


How to properly cut down trees can be looked up on a multitude of professional websites and sources, with demonstration videos galore. The knowledge is available to everyone....but the feeling is not. If you have no experience with it, I'd recommend hiring me. Thumb up

And thanks!
"Leave it to me to find a way to be,
Consider me a satellite forever orbiting,
I knew the rules but the rules did not know me, guaranteed." - Eddie Vedder
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#63
RE: Interesting snippet on Tx resistent depression.
(August 30, 2016 at 12:02 am)Arkilogue Wrote: I've completed a 3 month course of colon cleansing, body ph readjustment, and change of gut biome.  I directly experienced the difference in mood, emotion and mental clarity. I was like my body was rejoicing underneath me.  I've also experienced the decline of  natural elation and clarity as my diet turned back to crap. I have lived through what I assert.

There are several things wrong with this.  Firstly, your personal experience is not evidence.  For all you know you were experiencing the placebo effect.  Secondly, participating in a colon cleanse in no way qualifies you to speak out on psychiatric issues.  Thirdly, saying a colon cleanse helped you feel better does not get you even close to proving that the root cause of depression is a poor diet.

(August 30, 2016 at 12:02 am)Arkilogue Wrote: Does it take a PHD to know fresh food is good for you and processed food full of sugar and chemical preservatives is bad for you? I also link a number of medical doctors and specialist that said "your gut health does affect your overall sense of well being." Plus the science of how/why it affects you.  If you want to appeal to authority, it's all there to find.

BTW, do you know what you body does to protect itself against highly acidic stomach acid?

You're backtracking now to "fresh food is good for you," which is not what you claimed at all.  No one is denying that a good diet wouldn't be beneficial, but to say that proves that the root cause of depression is a poor diet is patently false.

Look, you can peddle your woo with your NDE's and your pseudo-scientific evidence, but when you start dispensing psychiatric advice, that's when you cross the line.  You need to stop.
Even if the open windows of science at first make us shiver after the cozy indoor warmth of traditional humanizing myths, in the end the fresh air brings vigor, and the great spaces have a splendor of their own - Bertrand Russell
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#64
RE: Interesting snippet on Tx resistent depression.
You're right, If I could edit the "the" to "a" I would. And you are oversimplifying what I have provided medical evidence from multiple sources for. And to hell with actually doing it and experiencing the difference first hand right? No one's personal experiences are proof of anything. Carry on.

Obviously depression can be caused by a multitude of factors. And this is one that few would think of and is worsened by drugs!

Don't listen to me, LISTEN TO THEM!

http://www.nytimes.com/2015/06/28/magazi....html?_r=0

http://www.apa.org/monitor/2012/09/gut-feeling.aspx
That gut feeling
With a sophisticated neural network transmitting messages from trillions of bacteria, the brain in your gut exerts a powerful influence over the one in your head, new research suggests.

Gut bacteria also produce hundreds of neurochemicals that the brain uses to regulate basic physiological processes as well as mental processes such as learning, memory and mood. For example, gut bacteria manufacture about 95 percent of the body's supply of serotonin, which influences both mood and GI activity.

When you consider the gut's multifaceted ability to communicate with the brain, along with its crucial role in defending the body against the perils of the outside world, "it's almost unthinkable that the gut is not playing a critical role in mind states," says gastroenterologist Emeran Mayer, MD, director of the Center for Neurobiology of Stress at the University of California, Los Angeles.




Want to talk about affecting mood and brain function? HOW ABOUT AUTISM???

http://www.theatlantic.com/health/archiv...in/395918/
When Gut Bacteria Changes Brain Function
Some researchers believe that the microbiome may play a role in regulating how people think and feel.

“There’s been an explosion of interest in the connections between the microbiome and the brain,” says Emeran Mayer, a gastroenterologist at the University of California, Los Angeles, who has been studying the topic for the past five years.

Some of the most intriguing work has been done on autism. For decades, doctors, parents, and researchers have noted that about three-quarters of people with autism also have some gastrointestinal abnormality, like digestive issues, food allergies, or gluten sensitivity. This recognition led scientists to examine potential connections between gut microbes and autism; several recent studies have found that autistic people’s microbiome differs significantly from control groups. The California Institute of Technology microbiologist Sarkis Mazmanian has focused on a common species called Bacteroides fragilis, which is seen in smaller quantities in some children with autism. In a paper published two years ago in the journal Cell, Mazmanian and several colleagues fed B. fragilis from humans to mice with symptoms similar to autism. The treatment altered the makeup of the animals’ microbiome, and more importantly, improved their behavior: They became less anxious, communicated more with other mice, and showed less repetitive behavior.

Read the rest of this article its comprehensive and fascinating. Oh and all you yogurt fans in the thread, you know who you are...this is for you from the same article.

To Mayer’s surprise, the results, which were published in 2013 in the journal Gastroenterology, showed significant differences between the two groups; the yogurt eaters reacted more calmly to the images than the control group. “The contrast was clear,” says Mayer. “This was not what we expected, that eating a yogurt twice a day for a few weeks would do something to your brain.” He thinks the bacteria in the yogurt changed the makeup of the subjects’ gut microbes, and that this led to the production of compounds that modified brain chemistry.




Moar you say, you want moar??? HAVE MOAR!!!

http://www.huffingtonpost.com/2015/01/04...91014.html
Now, promising new research from neurobiologists at Oxford University offers some preliminary evidence of a connection between gut bacteria and mental health in humans.The researchers found that supplements designed to boost healthy bacteria in the gastrointestinal tract (“prebiotics”) may have an anti-anxiety effect insofar as they alter the way that people process emotional information.

While probiotics consist of strains of good bacteria, prebiotics are carbohydrates that act as nourishment for those bacteria. With more evidence that gut bacteria may exert some influence on brain function and mental health, probiotics and prebiotics are being studied for the potential alleviation of anxiety and depression symptoms.

The results of one of the tests revealed that subjects who had taken the prebiotic paid less attention to negative information and more attention to positive information, compared to the placebo group, suggesting that the prebiotic group had less anxiety when confronted with negative stimuli. This effect is similar to that which has been observed among individuals who have taken antidepressants or anti-anxiety medication.

The researchers also found that the subjects who took the prebiotics had lower levels of cortisol — a stress hormone which has been linked with anxiety and depression — in their saliva when they woke up in the morning.

While previous research has documented that altering gut bacteria has a similarly anxiety-reducing effect in mice, the new study is one of the first to examine this phenomenon in humans. As of now, research on humans is in its early stages. A study conducted last year at UCLA found that women who consumed probiotics through regularly eating yogurt exhibited altered brain function in both a resting state and when performing an emotion-recognition task.

“Time and time again, we hear from patients that they never felt depressed or anxious until they started experiencing problems with their gut,” Dr. Kirsten Tillisch, the study’s lead author, said in a statement. “Our study shows that the gut–brain connection is a two-way street.”



http://link.springer.com/article/10.1007...014-3810-0
Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers

http://newsroom.ucla.edu/releases/changi...ugh-245617
Changing gut bacteria through diet affects brain function, UCLA study shows

The researchers were surprised to find that the brain effects could be seen in many areas, including those involved in sensory processing and not merely those associated with emotion, Tillisch said.

The knowledge that signals are sent from the intestine to the brain and that they can be modulated by a dietary change is likely to lead to an expansion of research aimed at finding new strategies to prevent or treat digestive, mental and neurological disorders, said Dr. Emeran Mayer, a professor of medicine (digestive diseases), physiology and psychiatry at the David Geffen School of Medicine at UCLA and the study's senior author.

"There are studies showing that what we eat can alter the composition and products of the gut flora — in particular, that people with high-vegetable, fiber-based diets have a different composition of their microbiota, or gut environment, than people who eat the more typical Western diet that is high in fat and carbohydrates," Mayer said. "Now we know that this has an effect not only on the metabolism but also affects brain function."

The UCLA researchers are seeking to pinpoint particular chemicals produced by gut bacteria that may be triggering the signals to the brain. They also plan to study whether people with gastrointestinal symptoms such as bloating, abdominal pain and altered bowel movements have improvements in their digestive symptoms which correlate with changes in brain response.

Meanwhile, Mayer notes that other researchers are studying the potential benefits of certain probiotics in yogurts on mood symptoms such as anxiety. He said that other nutritional strategies may also be found to be beneficial.

By demonstrating the brain effects of probiotics, the study also raises the question of whether repeated courses of antibiotics can affect the brain, as some have speculated. Antibiotics are used extensively in neonatal intensive care units and in childhood respiratory tract infections, and such suppression of the normal microbiota may have long-term consequences on brain development.

Finally, as the complexity of the gut flora and its effect on the brain is better understood, researchers may find ways to manipulate the intestinal contents to treat chronic pain conditions or other brain related diseases, including, potentially, Parkinson's disease, Alzheimer's disease and autism.

Answers will be easier to come by in the near future as the declining cost of profiling a person's microbiota renders such tests more routine, Mayer said.


And finally

http://www.scientificamerican.com/articl...n-the-gut/

Mental Health May Depend on Creatures in the Gut
The microbiome may yield a new class of psychobiotics for the treatment of anxiety, depression and other mood disorders


Scientists are increasingly convinced that the vast assemblage of microfauna in our intestines may have a major impact on our state of mind. The gut-brain axis seems to be bidirectional—the brain acts on gastrointestinal and immune functions that help to shape the gut's microbial makeup, and gut microbes make neuroactive compounds, including neurotransmitters and metabolites that also act on the brain.These interactions could occur in various ways: microbial compounds communicate via the vagus nerve, which connects the brain and the digestive tract, and microbially derived metabolites interact with the immune system, which maintains its own communication with the brain.

Microbes may have their own evolutionary reasons for communicating with the brain. They need us to be social, says John Cryan, a neuroscientist at University College Cork in Ireland, so that they can spread through the human population. Cryan's research shows that when bred in sterile conditions, germ-free mice lacking in intestinal microbes also lack an ability to recognize other mice with whom they interact. In other studies, disruptions of the microbiome induced mice behavior that mimics human anxiety, depression and even autism. In some cases, scientists restored more normal behavior by treating their test subjects with certain strains of benign bacteria.Nearly all the data so far are limited to mice, but Cryan believes the findings provide fertile ground for developing analogous compounds, which he calls psychobiotics, for humans. “That dietary treatments could be used as either adjunct or sole therapy for mood disorders is not beyond the realm of possibility,” he says.


Personality shifts

Scientists use germ-free mice to study how the lack of a microbiome—or selective dosing with particular bacteria—alters behavior and brain function, “which is something we could never do in people,” Cryan says. Entire colonies of germ-free mice are bred and kept in isolation chambers, and the technicians who handle them wear full bodysuits, as if they were in a biohazard facility. As with all mice research, extrapolating results to humans is a big step. That is especially true with germ-free mice because their brains and immune systems are underdeveloped, and they tend to be more hyperactive and daring than normal mice.

A decade ago a research team led by Nobuyuki Sudo, now a professor of internal medicine at Kyushu University in Japan, restrained germ-free mice in a narrow tube for up to an hour and then measured their stress hormone output. The amounts detected in the germ-free animals were far higher than those measured in normal control mice exposed to the same restraint. These hormones are released by the hypothalamic-pituitary-adrenal axis, which in the germ-free mice was clearly dysfunctional. But more important, the scientists also found they could induce more normal hormonal responses simply by pretreating the animals with a single microbe: a bacterium called Bifidobacterium infantis. This finding showed for the first time that intestinal microbes could influence stress responses in the brain and hinted at the possibility of using probiotic treatments to affect brain function in beneficial ways. “It really got the field off the ground,” says Emeran Mayer, a gastroenterologist and director of the Center for Neurobiology of Stress at the University of California, Los Angeles.

Meanwhile a research team at McMaster University in Ontario led by microbiologist Premsyl Bercik and gastroenterologist Stephen Collins discovered that if they colonized the intestines of one strain of germ-free mice with bacteria taken from the intestines of another mouse strain, the recipient animals would take on aspects of the donor's personality. Naturally timid mice would become more exploratory, whereas more daring mice would become apprehensive and shy. These tendencies suggested that microbial interactions with the brain could induce anxiety and mood disorders.


[Image: giphy.gif]
"Leave it to me to find a way to be,
Consider me a satellite forever orbiting,
I knew the rules but the rules did not know me, guaranteed." - Eddie Vedder
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#65
Interesting snippet on Tx resistent depression.
(August 30, 2016 at 12:02 am)Arkilogue Wrote: I've completed a 3 month course of colon cleansing, body ph readjustment, and change of gut biome.

LOL. Of COURSE you have! You play fast and loose with the boundaries of scientific evidence when it comes to theology; I'm not sure why I thought the liberties you take would be restricted to thatsubject in particular...

Quote:I directly experienced the difference in mood, emotion and mental clarity. I was like my body was rejoicing underneath me. I've also experienced the decline of natural elation and clarity as my diet turned back to crap. I have lived through what I assert.[quote]

Frankly, I don't care if you had your small intestine twisted into sailor's knots and now you think you can fly. Personal experience is not equivalent to expertise in ANY career field, health-related or otherwise. You do not count as your own case study. Either meet nationally accredited/required standards of education and training, or refrain from making recommendations. It's considered illegal in most states in the U.S. in fact, and for good reason.

[quote]Does it take a PHD to know fresh food is good for you and processed food full of sugar and chemical preservatives is bad for you? I also link a number of medical doctors and specialist that said "your gut health does affect your overall sense of well being." Plus the science of how/why it affects you. If you want to appeal to authority, it's all there to find.

Firstly, you understand that using blanket terminology like "processed foods", "chemical preservatives", and "bad for you" is a gross oversimplification and wholly unscientific, yes?

Second, you did more than just infer from the available evidence that there is a relationship between the gut microbiome and human health. You asserted an oversimplified cause and effect relationship between it and depression that has not been established by scientific research.

Quote:do you know what you body does to protect itself against highly acidic stomach acid?

Yes, I do. Thanks. I got really good grades in school and everything. What is the point?

Also, I find it pretty ironic that someone so concerned with the science behind gut health would undergo such a ridiculous procedure as a colonic, considering there is no good evidence to support that it has any positive effects on human health, and in fact comes with many risks including: dehydration, electrolyte imbalance, and depletion of the BENEFICIAL microflora that already populate your colon. Intestinal cells regenerate every 3 days or so. Thanks evolution. There is no need to artificially "clean" them.




Nay_Sayer: “Nothing is impossible if you dream big enough, or in this case, nothing is impossible if you use a barrel of KY Jelly and a miniature horse.”

Wiser words were never spoken. 
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#66
Interesting snippet on Tx resistent depression.



I find it funny how you thought that was a "mic drop" moment in any capacity, as though you've actually scientifically "proved" something..


I don't care about preliminary or "promising" research in the context of this thread, Ark. There exists a plethora of preliminary research describing the potential mechanisms by which healthy gut flora can positively effect human health. No one is disputing that.

You made a cause-and-effect claim about gut flora and depression. It is up to you to provide us with the robust body of high quality, double-blind, controlled, clinical trials (on humans, not mice) that have established this cause-and-effect relationship to such a degree of certainty in the scientific community, that its use as treatment is reflected in the well-described standards of practice set forth by any and all relevant health organizations.

You can't do that. Because, the research isn't there yet. It may not be there in 10 years. It may not ever be there. And until it is, you DON'T make treatment recommendations for illnesses. This is called, "being a professional in your field of expertise."
Nay_Sayer: “Nothing is impossible if you dream big enough, or in this case, nothing is impossible if you use a barrel of KY Jelly and a miniature horse.”

Wiser words were never spoken. 
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#67
RE: Interesting snippet on Tx resistent depression.
(Hey guys, how do you use "hide tags"?)
Nay_Sayer: “Nothing is impossible if you dream big enough, or in this case, nothing is impossible if you use a barrel of KY Jelly and a miniature horse.”

Wiser words were never spoken. 
Reply
#68
RE: Interesting snippet on Tx resistent depression.
ala

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I am the Infantry. I am my country’s strength in war, her deterrent in peace. I am the heart of the fight… wherever, whenever. I carry America’s faith and honor against her enemies. I am the Queen of Battle. I am what my country expects me to be, the best trained Soldier in the world. In the race for victory, I am swift, determined, and courageous, armed with a fierce will to win. Never will I fail my country’s trust. Always I fight on…through the foe, to the objective, to triumph overall. If necessary, I will fight to my death. By my steadfast courage, I have won more than 200 years of freedom. I yield not to weakness, to hunger, to cowardice, to fatigue, to superior odds, For I am mentally tough, physically strong, and morally straight. I forsake not, my country, my mission, my comrades, my sacred duty. I am relentless. I am always there, now and forever. I AM THE INFANTRY! FOLLOW ME!
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#69
RE: Interesting snippet on Tx resistent depression.
(August 30, 2016 at 10:31 am)Rhythm Wrote: ala

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Thank you, sir!
Nay_Sayer: “Nothing is impossible if you dream big enough, or in this case, nothing is impossible if you use a barrel of KY Jelly and a miniature horse.”

Wiser words were never spoken. 
Reply
#70
RE: Interesting snippet on Tx resistent depression.
(August 30, 2016 at 9:46 am)LadyForCamus Wrote: Yes, I do.  Thanks.  I got really good grades in school and everything.   What is the point?

Also, I find it pretty ironic that someone so concerned with the science behind gut health would undergo such a ridiculous procedure as a colonic, considering there is no good evidence to support that it has any positive effects on human health, and in fact comes with many risks including: dehydration, electrolyte imbalance, and depletion of the BENEFICIAL microflora that already populate your colon.  Intestinal cells regenerate every 3 days or so.  Thanks evolution.  There is no need to artificially "clean" them.  

Never went through a "colonic". I spent one month cutting out all acidic foods and the next two taking an increasing amount of specific herbs that break up and loosen the mucoid plaque our body creates to protect itself from it's own low ph stomach acids. I passed a good 15-20 feet of this stuff and it is not normal fecal matter. It's like tire rubber, a biofilm that sticks to the walls of the intestines and you'd have a hard time cutting through it with a steak knife. I was also taking probiotics.

Mucoid plaque a massive habitat for what ever can colonize it. It blocks the inner surface of the intestines from receiving nutrients and because the feeding of the organs/tissue/etc is area specific, the organ/tissue is not only under nourished but being auto-intoxicated by a giant bacterial mat.

I knew the days I was going to pass a piece as I'd woke up groggy, grumpy and irritated. And that mind state feeling changed very quickly to peaceful when it came out. Why? because it's no longer a massive, loosened source of toxic material traveling through my second brain. But to hell with personal experience right?

The herb program I use was developed by an American doctor in concert with a Native American medicine man. http://www.ariseandshine.com/whole-body-...d-out.html

"After 4 or 5 days eating these Wild Salads they both experienced a 'clearing out' that could only be described as extraordinary, evidenced by great lengths of rope-like mucoid plaque from the alimentary canal. Their convalescence was rapid with their overall well being improving above and beyond their previous states of health; vastly beyond any cleansing, fasting or juice fasting they had ever achieved."

But to hell with their personal experiences right? Can't be trusted. I'm sure Big Pharma Consensus Authority will tell us what we're supposed to do with ourselves.
"Leave it to me to find a way to be,
Consider me a satellite forever orbiting,
I knew the rules but the rules did not know me, guaranteed." - Eddie Vedder
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