The laws of thermodynamics

[brewer]

I don't think that mathematicians have problems describing such structures, only visualizing them directly, which is true of all of us.  I know that Albert Einstein worked on a 5-dimensional TOE; a picture of him at a blackboard with some other mathematical physicists is out there somewhere.

No difficulty at all describing them.

Most people can't *really* visualize 3D, let alone 5D. But 5D isn't that hard: just think in 4D and add one dimension.