Nobody sane can make a positive claim about the supernatural, I think, because all of the effects we can observe are within our natural world limits and science works by trying to fit/explain these effects within the natural world. Frankly we know very little about the natural world itself to draw even a vague boundary around it, and hence it is impossible to even speculate on the supernatural based on this knowledge, which by definition is beyond the natural realm.
Quote:To know yet to think that one does not know is best; Not to know yet to think that one knows will lead to difficulty.
- Lau Tzu
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