(December 5, 2015 at 7:35 pm)Quantum Wrote:(December 5, 2015 at 7:22 pm)AAA Wrote: correct base simply meaning the one of the four that yields functionality. The calculation is simply to see if it is reasonable to believe that point mutations could add a new functional sequence. It is essentially that you have around 100 amino acids in a typical protein. Each amino acid comes from 3 bases. Each base has a 1 in 4 chance of being the one that yields the appropriate amino acid to try to make a functional protein. These have to all happen in a sequence with no (or very few) misses. 300^1/4 is an oversimplification of the calculation I have tried to do. There are other variables but this
Are you seriously trying to say that there is exactly one unique sequence of bases that makes a functional protein?
That's silly.
No, there are a lot of functional sequences, but they have to have a specific order of the bases. And they are rare.