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Gene therapy restores sight in mice.
#2
RE: Gene therapy restores sight in mice.
(December 22, 2020 at 10:02 pm)brewer Wrote: Gene carried by adeno-associated virus is delivered to the target cells.

"A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy, according to The National Eye Institute, which provided an SBIR grant to Nanoscope for development of MCO1. The company is planning a clinical trial for later this year."

"A variety of common eye diseases, including age-related macular degeneration and retinitis pigmentosa, damage the photoreceptors, impairing vision. But while the photoreceptors may no longer fully function, other retinal neurons (bipolar cells) remain intact. The team identified a way for bipolar cells to take on some of the work of damaged photoreceptors."

https://www.genengnews.com/news/gene-the...n-in-mice/

Very good news. RP was pretty common in my family in the previous generation as well as the one before that.  It appears to have run its course in the family tree, thankfully.  But I watched relatives deal with their advancing blindness and there being nothing that could be done about it.
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Messages In This Thread
Gene therapy restores sight in mice. - by brewer - December 22, 2020 at 10:02 pm
RE: Gene therapy restores sight in mice. - by arewethereyet - December 22, 2020 at 10:06 pm
RE: Gene therapy restores sight in mice. - by Fireball - December 22, 2020 at 10:57 pm
RE: Gene therapy restores sight in mice. - by brewer - December 22, 2020 at 11:22 pm
RE: Gene therapy restores sight in mice. - by Fireball - December 23, 2020 at 12:07 am
RE: Gene therapy restores sight in mice. - by arewethereyet - December 22, 2020 at 11:33 pm
RE: Gene therapy restores sight in mice. - by Brian37 - December 22, 2020 at 10:22 pm
RE: Gene therapy restores sight in mice. - by arewethereyet - December 22, 2020 at 10:25 pm
RE: Gene therapy restores sight in mice. - by Angrboda - December 22, 2020 at 10:28 pm
RE: Gene therapy restores sight in mice. - by Brian37 - December 22, 2020 at 10:30 pm

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